The clinical course is usually characterized by severe neurological afflictions followed by remissions and in some cases tend to be progressive to death. It also revises the different alternatives of medical and rehabilitation treatments. It has a wide clinical spectrum from benign to malignant forms. Please use one of the following formats to cite this article in your essay, paper or report. The loss of brain volume, or brain atrophy, has been classically considered as a marker present in severe or advanced stages of the. Multiple sclerosis is the main cause of neurological disability in young adults. Childhood body mass index and multiple sclerosis risk. It is the leading cause of disability in this group. The purpose of this paper is to revise the current concepts of multiple sclerosis ms on its diverse ways of manifestation, its progression and its prognosis. Multiple sclerosis is an autoimmune disease that affects the central nervous system, most common in young people aged 2050 years. The molecular basis of nutritional intervention in multiple sclerosis. The clinical course is usually characterized by severe. Axonal degeneration is thought to be responsible for the irreversible progression of the disability seen in affected patients 2, 3, 4. Expression of metabotropic glutamate receptors in multiple sclerosis brain.
Multiple sclerosis ms is recognized as an inflammatory and neurodegenerative disease of the central nervous system cns 1. Multiple sclerosis is the most common inflammatory, chronic and degenerative condition of the central nervous system, and represents the first cause of disability in young adults. Colombia, drug costs, economic, epidemiology, multiple sclerosis, prevalence mesh. Multiple sclerosis is an autoimmune, inflammatory and desmyelinization disease of central nervous system cns of unknown etiology and critical evolution. Hospital almenara, 20012015 clinical changes of multiple sclerosis according to modification of the mcdonald criteria. Multiple sclerosis, loss of functionality and gender. In mexico, 11 to 20 out of every 100 000 people suffer from this disease. Multiple sclerosis abstract since more than 100 years carswell, cruveilhier and specially charcot who in 1868 offered the first description about sclerosis in plaques, until today, multiple sclerosis is a challenge to doctors and investigators who treat it. In cuba, a tropical region considered of low prevalence, there are approximately from 550 to 1 650 patients.
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